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3 Translational decision framework for VLP vaccine engineering The four evaluative dimensions introduced in Sections “2.1 Extra-VLP protein antigen display technologies” and “2.2 Intra-VLP nucleic acid encapsulation technologies”–cargo flexibility, loading specificity, functional efficiency, and manufacturability–converge into a translational design logic integrating antigen display and nucleic acid encapsulation within a unified development pathway for rational VLP vaccine engineering (Figure 4)

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and 22074099, F.L.), the Fundamental Research Funds for the Central Universities (No

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